Description
Product Characteristics: For the quantitative determination of human beta-klotho (KLB) concentrations in serum, plasma, tissue homogenates, cell lysates.
Target Information: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity)